Mu.Ta.Lig - COST ACTION CA15135

Dr. Zarko MITIC

14 June 2016
admin

zarko

General information

Name: Žarko
Surname: Mitić
E-mail: zak_chem2001@yahoo.com
Cell phone number with international prefix: +381641318606
Country: Serbia
Affiliation: University of Niš, Faculty of Medicine, Department of Chemistry
Gender: F □ M ☒
Year of the PhD title: 2009.
Personal web page:

http://vihos.masfak.ni.ac.rs/site/index.php/partners/89-university-of-nis-faculty-of-medicine-serbia

https://www.npao.ni.ac.rs/medicinski-fakultet/686-zarko-mitic
Previous COST participation: No ☒ Yes □

 

List of 10 selected publications within last 5 years

  1. Ž. Mitić, M. Cakić, G.M. Nikolić, R. Nikolić, G.S. Nikolić, R. Pavlović, E. Santaniello, Synthesis, physicochemical and spectroscopic characterization of copper(II)-polysaccharide pullulan complexes by UV–vis, ATR-FTIR, and EPR, Carbohydrate Research, 346(3) (2011), 434–441. IF (2011) 2.332
  1. M. Cakić, Ž. Mitić, G. Nikolić, I. Savić, I. Savić, Design and optimization of drugs used to treat copper deficiency, Expert Opinion on Drug Discovery, 8(10) (2013), 1253–1263. IF (2013) 3.467
  1. M. Barbeck, S. Najman, S. Stojanović, Ž. Mitić, J. M. Živković, J. Choukroun, P. Kovačević, R. Sader, C. J. Kirkpatrick, S. Ghanaati, Addition of blood to a phycogenic bone substitute leads to increased in vivo vascularization, Biomedical Materials, 10 (2015) 055007, 1–15. IF (2014) 3.697
  1. N. Ignjatović, S. Vranješ Djurić, Ž. Mitić, D. Janković, D. Uskoković, Investigating an organ-targeting platform based on hydroxyapatite nanoparticles using a novel in situ method of radioactive 125Iodine labeling. Material Science and Engineering C, 43 (2014), 439–446. IF(2014) 3.088
  1. Ž.J. Mitić, S.J. Najman, M.D. Cakić, Z.R. Ajduković, N.L. Ignjatović, R.S. Nikolić, G.M. Nikolić, S.T. Stojanović, M.Đ. Vukelić, M.D. Trajanović, Spectroscopic characterization of bone tissue of experimental animals after glucocorticoid treatment and recovery period, Journal of Molecular Structure, 1074 (2014) 315–320. IF(2014) 1.602
6.       M.Đ. Vukelić, Ž.J. Mitić, M.S. Miljković, J.M. Živković, N.L. Ignjatović, D.P. Uskoković, J.Ž. Živanov-Čurlis, P.J. Vasiljević, S.J. Najman, Apatite formation on nanomaterial calcium phosphate/poly-dl-lactide-co-glycolide in simulated body fluid, Journal of Applied Biomaterials and Biomechanics,10(1) (2012), 43–48. IF (2012) 1.542
7.       Ž. Mitić, M. Cakić, G. Nikolić, Fourier-Transform IR spectroscopic investigations of Cobalt(II)-dextran complexes by using D2O isotopic exchange, Spectroscopy Int. J., 24(3,4) (2010), 269–275. IF(2010) 0.932
8.       Ž. Mitić, G.S. Nikolić, M. Cakić, P. Premović, Lj. Ilić, FTIR spectroscopic characterization of Cu(II) coordination compounds with exopolysaccharide pullulan and its derivatives, Journal of Molecular Structure, 924–926 (2009), 264–273. IF(2009) 1.551
9.       M. Cakić, Ž. Mitić, G.S. Nikolić, Lj. Ilić, G.M. Nikolić, The investigations of bioactive copper(II) complexes with reduced low–molar dextran, Spectroscopy Int. J., 22(2–3) (2008), 177–185. IF(2008) 0.820
10.    G.S. Nikolić, M. Cakić, Ž. Mitić, B. Ilić, P. Premović, Attenuated Total Reflectance–Fourier Transform Infrared microspectroscopy of copper(II) complexes with reduced dextran derivatives, Russian Journal of Physical Chemistry A, 83(9) (2009), 1520–1525. IF(2009) 0.438

 

Main skills and expertise (up to 5)

1. Fourier Transform Infrared (FTIR) spectroscopy and ATR-FTIR microspectroscopy
2. SEM-EDX spectroscopy
3. UV-Vis spectrophotometry
4. 1H-NMR and 13C-NMR spectroscopy
5.ESR spectroscopy

 

Main equipment/facilities available in the participants’ lab (up to 5)

1. FTIR and ATR-FTIR
2. SEM-EDX
3. UV-Vis
4. MALDI-TOF-TOF MS
5. HPLC

 


 

Short personal activity proposal for the COST Action CA15135 (max 1000 characters)

Within COST action CA15135 my research will include

 

1.      Spectroscopic characterization of biological active molecules and synthesized drugs by using:

·         FTIR spectroscopy and ATR-FTIR microspectroscopy,

·         SEM-EDX spectroscopy,

·         MALDI-TOF-TOF MS spectrometry,

·         UV-Vis spectrophotometry.

2.      Chromatographic separation and characterization of biological active molecules and synthesized drugs by using:

·         HPLC chromatography.

3.      Chemoinformatic related research:

·         Development of QSAR methods and models based on Monte Carlo method and other machine learning techniques with Random forest as a main method,

·         Development of new topological and molecular fragment based descriptors for QSAR modeling,

·         The application of developed QSAR models for computer aided drug design.

4.      Chemometry related research:

·         Further development and application of Multivariate Curve Resolution Alternating Least Squares (MCR-ALS).

 

Work Group preference: score from 1 (preferred) to 4 (not preferred)

Work Group of the CA15135 COST Action Score
WG1: Development of new chemical entities 2
WG2: Selection of biological targets and assessment of biological data 3
WG3: Development of chemical databases 2
WG4: Development of Computational methods for multiple ligand design and discovery 1
MC Substitute, Serbia, wg4