General information
| Name: Hanoch |
| Surname: Senderowitz |
| E-mail: hsenderowitz@gmail.com; hanoch.senderowitz@biu.ac.il |
| Cell phone number with international prefix: +972542233076 |
| Country: Israel |
| Affiliation: Bar-Ilan University |
| Gender: F □ M X |
| Year of the PhD title: 1993 |
| Personal web page: http://www1.biu.ac.il/indexE.php?id=7744&pt=30&pid=7703&level=2&cPath=7702,7703,7744 |
List of 10 selected publications within last 5 years
| 1. Kahazanov, N.; Iline-Vul, T.; Noy, E.; Goobes, G.; Senderowitz, H. Design of Cellulose Binding Peptides as Carriers for Catalytic Degradation of Cellulose Inspired by the Cellulose Binding Domain from T. Reesei, J. Phys. Chem. B. 2016, 120, 309-19. |
| 2. Nahum O. E.; Yosipof, A. Senderowitz, H. A Multi-Objective Genetic Algorithm for Outlier Removal, J Chem. Inf. Model. J. Chem. Inf. Model., 2015, 55, 2507-2518. |
| 3. Avgy-David, H.; Senderowitz, H. Towards Focusing Conformational Ensembles on Bioactive Conformations: A Molecular Mechanics / Quantum Mechanics Study, J. Chem. Inf. Model. 2015, 55, 2154–2167. |
| 4. Gilad, Y; Nadassy Katalin; Senderowitz, H. A reliable computational protocol for the selection of optimal screening libraries, J. Chemoinformatics, 2015, Dec 11;7:61. doi: 10.1186/s13321-015-0108-0. eCollection 2015. |
| 5. Momic, T.; Katzehendler, J.; Shai, E.; Varon, D.; Noy, E.; Senderowitz, H.; Eble, J. A.; Marcinkiewicz, C.; Lazarovici, P. Vipegitide a folded peptidomimetic partial antagonist of α2β1 integrin with anti-platelet aggregation activity, Drug Design, Development and Therapy, 2015, 10, 850-61. |
| 6. Yosipof, A.; Senderowitz, H. k-Nearest Neighbors optimization based outlier removal. J. Comput. Chem. 2015, 36, 493-506. |
| 7. Kahremany, S.; Livne, A.; Gruzman, A.; Senderowitz, H.; Sasson S. Activation of Peroxisome Proliferator Activator Receptor-δ: from computer modeling to biological effects, Br. J. Pharmacol. 2015 172, 754-70. |
| 8. Nadel, Y.; Gliad, Y.; Lecka, J.; Ben-David, G.; Sendrowitz, H.; Sévigny, J. Förster, D.; Reiser, G.; Camden, J.; Weisman, G. A.; Fischer, B, Highly potent and selective NPP1 inhibitors based on ATP – (α or γ) thio – (α,β or β,γ)-methylene scaffold. J. Med. Chem. 2014 57, 4677-91. |
| 9. Gilad, Y.; Senderowitz, H. Docking Studies on DNA Intercelators J. Chem. Inf. Model. 2014, 54, 96-107. |
| 10. Noy, E.; Senderowitz, H. Molecular simulations for the evaluation of binding free energies in lead optimization Drug Development Research, 2011, 72, 36-44 |
Main skills and expertise (up to 5)
| 1. Computational Chemistry |
| 2.Molecular Modeling |
| 3.Computer aided drug design |
| 4. Chemoinformatics |
| 5. Cystic Fibrosis |
Main equipment/facilities available in the participants’ lab (up to 5)
| 1.A computational cluster of ~300 cores |
| 2.Software (BIOVIA, Schrodinger, Autodock, GROMACS, NAMD, Amber) |
| 3. |
| 4. |
| 5. |
Short personal activity proposal for the COST Action CA15135 (max 1000 characters)
Work Group preference: score from 1 (preferred) to 4 (not preferred)
| Work Group of the CA15135 COST Action | Score |
| WG1: Development of new chemical entities | 4 |
| WG2: Selection of biological targets and assessment of biological data | 2-3 |
| WG3: Development of chemical databases | 2-3 |
| WG4: Development of Computational methods for multiple ligand design and discovery | 1 |
